{"id":540,"date":"2025-10-08T23:33:42","date_gmt":"2025-10-08T23:33:42","guid":{"rendered":"https:\/\/sites.ohio.edu\/nielsen-corinne\/home\/"},"modified":"2026-02-18T16:57:26","modified_gmt":"2026-02-18T16:57:26","slug":"home","status":"publish","type":"page","link":"https:\/\/sites.ohio.edu\/nielsen-corinne\/","title":{"rendered":"Home"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"540\" class=\"elementor elementor-540\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2cb5f4f e-flex e-con-boxed e-con e-parent\" data-id=\"2cb5f4f\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-fe6a729 e-con-full e-flex e-con e-child\" data-id=\"fe6a729\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-de48581 elementor-widget elementor-widget-heading\" data-id=\"de48581\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Studying Mammalian Neurovascular Development and <br>Pathophysiology<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8966e55 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"8966e55\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c7345d2 elementor-widget elementor-widget-heading\" data-id=\"c7345d2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">The Nielsen Lab<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7ba1da6 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"7ba1da6\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/sites.ohio.edu\/nielsen-corinne\/research\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Learn More<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-556ef17 e-flex e-con-boxed e-con e-parent\" data-id=\"556ef17\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-40552d9 e-con-full e-flex e-con e-child\" data-id=\"40552d9\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2fa8427 elementor-widget elementor-widget-heading\" data-id=\"2fa8427\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">About Our Research<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e9a8110 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"e9a8110\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0e50bf9 e-con-full e-flex e-con e-child\" data-id=\"0e50bf9\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1277452 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"1277452\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Interdependent development and functions of the mammalian nervous and vascular systems are tightly coordinated. The brain vasculature provides a critical and expansive blood supply to support neuronal metabolism and function, and vascular lesions within the brain are often accompanied by neurological dysfunction. Our lab is interested in understanding how these systems influence one another \u2013 e.g., how diverse neural and vascular cell populations respond to cues from one another. The lab currently studies neurovascular regulation in the context of brain arteriovenous malformation (AVM), a human vascular disease characterized by direct delivery of blood from artery to vein (without intervening capillaries), vessel entanglements, and often accompanied by neurological deficit. We are using genetic models of brain AVM to determine molecular and cellular mechanisms that regulate neurovascular development and function \u2013 and mechanisms involved in neurovascular pathogenesis \u2013 using mouse genetics, molecular and cell biological, and imaging approaches.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Studying Mammalian Neurovascular Development and Pathophysiology The Nielsen Lab Learn More About Our Research Interdependent development and functions of the mammalian nervous and vascular systems are tightly coordinated. The brain vasculature provides a critical and expansive blood supply to support neuronal metabolism and function, and vascular lesions within the brain are often accompanied by neurological [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_eb_attr":"","site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"enabled","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-540","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/pages\/540","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/comments?post=540"}],"version-history":[{"count":10,"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/pages\/540\/revisions"}],"predecessor-version":[{"id":1894,"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/pages\/540\/revisions\/1894"}],"wp:attachment":[{"href":"https:\/\/sites.ohio.edu\/nielsen-corinne\/wp-json\/wp\/v2\/media?parent=540"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}