Yang V. Li, M.D., Ph.D.
Professor of Neuroscience
Department of Biomedical Sciences
346 Irvine Hall


Selected Publications

Stork CJ, Li YV. Elevated cytoplasmic free zinc and increased reactive oxygen species (ROS) generation in the context of brain Iinjury. Acta Neurochir Suppl. 2016;121:347-53.

Sun BL, He MQ, Han XY, Sun JY, Yang MF, Yuan H, Fan CD, Zhang S, Mao LL, Li DW, Zhang ZY, Zheng CB, Yang XY, Li YV, Stetler RA, Chen J, Zhang F. Intranasal Delivery of Granulocyte Colony-Stimulating Factor Enhances Its Neuroprotective Effects Against Ischemic Brain Injury in Rats. Mol Neurobiol. 2016 Jan;53(1):320-30.

Lu Q, Haragopal, H, Slepchenko KG, Stork CJ,  Li YV. Intracellular zinc distribution in mitochondria, ER and the Golgi apparatus. Journal of Molecular Signaling in print.

Lu Q, Slepchenko, K,  LI YV. Zinc chelation reduces the generation of reactive oxygen species induced by hypoxia. Program No. 402.17. Neuroscience 2015 Abstracts. Washington DC: Society for Neuroscience, 2016 Online.

Yu X., LI YV. Metal ion chelation enhances tissue plasminogen activator (tPA)-induced thrombolysis: an in vitro and in vivo study. Program No. 651.07. Neuroscience 2015 Abstracts. Washington DC: Society for Neuroscience, 2016 Online.

Metal ions in Stroke” by Yang V Li and John H Zhang (eds), Publisher: Springer, New York. 2012 edition. http://www.springer.com/biomed/neuroscience/book/978-1-4419-9662-6

Yang V Li, John H Zhang “Metal Ions in Stroke Pathophysiology” (Chapter one) In Metal Ion in Stroke, Yang V Li, John H Zhang (eds), pp 1-12, Publisher: Springer; 2012 edition.

Yang V LiZinc overload in stroke” (Chapter seven) In Metal Ion in Stroke, Yang V Li, John H Zhang (eds), pp 167-190, Publisher: Springer; 2012 edition (May 31, 2012)

Yu X, Li YV*. Neuroprotective effect of zinc chelator DEDTC in a zebrafish (Danio rerio) model of hypoxic brain injury. Zebrafish,2013 Mar;10(1):30-5.

Slepchenko KG, Li YV. Rising intracellular zinc by membrane depolarization and glucose in insulin-secreting clonal HIT-T15 beta cells. Experimental Diabetes Research. 2012;2012:190309. Epub 2012 Mar 21.

Yu X, Li YV*. Zebrafish as an alternative model for hypoxic-ischemic brain damage. Int J Physiol Pathophysiol Pharmacol. 2011;3(2):88-96. Epub 2011 Apr 20.

Stork CJ, Li YV. Exploiting the liberation of Zn2+  to measure cell viability. Methods in Molecular Biology. 2011;740:157-63.

Stork CJ, Li YV*. Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neurons. Journal of Molecular Signaling. 2010 May 26;5:5.

Martorano LM, Stork CJ, Li YV*. UV irradiation-induced zinc dissociation from commercial zinc oxide sunscreen and its action in human epidermal keratinocytes. Journal of Cosmetic Dermatology. 2010 Dec;9(4):276-86.

Christian J. Stork & Yang V. Li, Rising zinc: a significant cause of ischemic neuronal death in the CA1 region of rat hippocampus. J Cereb Blood Flow Metab. 2009 Jun 3. [Epub ahead of print]

Joshua Ketterman & Yang V. Li, Presynaptic evidence for zinc release at the mossy fiber synapse of rat hippocampus. J Neuroscience Research. 2008 Feb 1;86(2):422-334

Chinthasagar Bastian & Yang V. Li, Fluorescence imaging study of extracellular zinc at the hippocampal mossy fiber synapse. Neuroscience Letter. 2007 May 29;419(2):119-24. Epub 2007 May 4.

Christian J. Stork & Yang V. Li, Intracellular zinc elevation measured with a "calcium-specific" indicator during ischemia and reperfusion in rat hippocampus: a question on calcium overload.  The Journal of Neuroscience.  2006 Oct 11;26(41):10430-7.


Jennifer L. Martin, Christian J. Stork, & Yang V. Li, Determining zinc with commonly used calcium and zinc fluorescent indicators, a question on calcium signals. Cell Calcium. 2006 Oct;40(4):393-402. Epub 2006 Jun 9.


Caleb O. Molokwu & Yang V. Li, Zinc homeostasis and bone mineral density. Ohio Research and Clinical Review. Fall 2006;15:7-15. COVER


Christian J. Stork & Yang V. Li, Measuring cell viability with membrane impermeable zinc fluorescent indicator. Journal of Neuroscience Methods. 2006 Sep 15;155(2):180-6. Epub 2006 Feb 8.


Guo Wei, Christopher J. Hough, Yang Li, John M. Sarvey (2004) Characterization of extracellular accumulation of Zn2+ during ischemia and reperfusion of hippocampus slices in rat. Neuroscience. 125(4):867-77.

Yang V. Li, Christopher J. Hough & John M. Sarvey (2003) Do we need zinc to think? Science STKE, pe19 (review).

Yang Li, Christopher J. Hough, Christopher J. Frederickson & John M. Sarvey (2001) Induction of Mossy Fiber-CA3 LTP Requires Translocation of Synaptically Released Zn2+, Journal of Neuroscience. Oct 15;21(20):8015-25.

Yang Li, Christopher J. Hough, Sang Wan Suh, John M. Sarvey & Christopher J. Frederickson (2001) Rapid Translocation of Zn2+ from Nerve Terminals into Postsynaptic Hippocampal Neurons Following Physiological Stimulation, Journal of Neurophysiology. Nov;86(5):2597-604.PDF full text

Yang Li, Lynne A. Holtzclaw, James T. Russell, (2001) Müller cell Ca2+ waves evoked by purinergic agonists in freshly isolated rat retinal slices. Journal of Neurophysiology, 85(2):986-994.

Yang Li, M. Steven Evans, Carl L. Faingold, (1999) Synaptic response patterns of neurons in the cortex of rat inferior colliculus. Hearing Research. Nov;137(1-2):15-28.

Yang Li, M. Steven Evans, Carl L. Faingold, (1998) A comparison of electrophysiological properties in three subnuclei of rat inferior colliculus in vitro. Hearing Research. Jul;121(1-2):1-10.

Yang Li, M. Steven Evans, Carl L. Faingold, (1994) Inferior colliculus neuronal membrane and synaptic properties in genetically epilepsy-prone rats. Brain Research, 660:232-240.


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Last updated: 09/11/2017